The original article was provided by Copan USA.
In the intricate landscape of medical diagnostics, unravelling the mysteries of gastrointestinal (GI) pathogens poses a significant challenge. The traditional methods, relying on unpreserved or Cary-Blair preserved stools, have been the norm. However, our diagnostic odyssey explores an alternative avenue – the Copan FecalSwab®.
The backdrop of our study is set against the canvas of the BD MAX™ Enteric Bacterial Panel and BD MAX™ Extended Enteric Bacterial Panel (BDM GIP) – sophisticated multiplex PCR tests capable of detecting up to eight different GI pathogens. Unlike the conventional approaches, the Copan FecalSwab® introduces a pragmatic alternative, utilizing Cary-Blair medium for specimen preservation.
Materials & Methods: Crafting Precision in Diagnostics
Our quest for efficiency led us to meticulously evaluate the FecalSwab® preserved stool specimens in tandem with BDM GIP. Negative stool samples, artfully inoculated with strains representing each BDM GIP target, took center stage. The performance was scrutinized on the BD MAX™ System, using varied input volumes (10 µl, 25 µl, and 50 µl) for FecalSwab® and the recommended volumes for Para-Pak.
Results: The Symphony of Diagnostic Precision
As the data unfolded, a pivotal revelation emerged – 50 µl of FecalSwab® stool-preserved samples stood out as the optimal volume for BDM GIP. The real-world applicability shone through as 93 out of 139 clinical samples displayed positivity for at least one BDM GIP target. A symphony of results unfolded, showcasing a remarkable 100% agreement between FecalSwab® and Para-Pak.
Discussion: A Paradigm Shift in Gastrointestinal Pathogen Detection
The traditional narrative of using Cary-Blair preserved stools is met with a transformative alternative – the Copan FecalSwab®. This study not only determines the ideal FecalSwab® volume but also positions it as an equivalent performer to the recommended Meridian Para-Pak® Cary-Blair medium for the BD MAX GI Panels.
Conclusion: The Echoes of Diagnostic Simplicity
In the complex realm of GI pathogen detection, the Copan FecalSwab® emerges as a beacon of simplicity and effectiveness. This user-friendly alternative to stool sample testing not only simplifies the diagnostic process but also underscores the importance of innovation in the realm of medical diagnostics. As we conclude our diagnostic odyssey, the Copan FecalSwab® stands tall, offering a pragmatic and effective solution in the ever-evolving landscape of medical diagnostics.
Date April 13, 2019
Conference or Journal Poster Presented at the 2019 ECCMID Meeting in Amsterdam, Netherlands
Author(s) Suzane Silbert Hanen Fernandez Rojas Carly Kubasek Alicia Gostnell Ray Widen
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